Alexander Isak has been dropped by Newcastle ahead of their trip to Aston Villa with speculation rife their star striker is on the verge of a move to Liverpool, while Yoane Wissa has been left out of Brentford's squad as Newcastle are reportedly set to make an improved bid for the player. But who else is missing this weekend?
Scroll down below to find out who's missing and who is unlikely to feature ahead of the opening round of Premier League fixtures:
Liverpool v Bournemouth (Friday, 21:00 CET)
WON'T PLAY
Bajcetic S. | Hamstring Injury
Chambers L. | Back Injury
Gomez J. | Achilles Tendon Injury
Gravenberch R. | Red Card
Scanlon C. | Hamstring Injury
Williams R. | Injury
Christie R. | Groin Injury
Cook L. | Knee Injury
Kluivert J. | Calf Injury
Unal E. | Knee Injury
DOUBTFUL
Bradley C. | Muscle Injury
Ouattara Da. | Health problems
Sinisterra L. | Muscle Injury
Aston Villa v Newcastle (Saturday, 13.30 CET)
WON'T PLAY
Martinez E. | Red Card
Isak A. | Suspended
Willock J. | Calf Injury
DOUBTFUL
Barkley R. | Knock
Garcia A. | Knock
Rogers M. | Ankle Injury
Brighton v Fulham (Saturday, 16:00 CET)
WON'T PLAY
Enciso J. | Knee Injury
March S. | Knee Injury
Webster A. | Knee Injury
Robinson A. | Knee Injury
DOUBTFUL
Baleba C. | Knee Injury
Hinshelwood J. | Knock
Kostoulas C. | Lacking Match Fitness
Sessegnon R. | Injury
Sunderland v West Ham (Saturday, 16:00 CET)
WON'T PLAY
Alese A. | Broken Leg
Cirkin D. | Wrist Injury
Hjelde L.F. | Achilles Tendon Injury
Mundle R. | Hamstring Injury
O'Nien L. | Shoulder Injury
Earthy G. | Injury
Summerville C. | Hamstring Injury
DOUBTFUL
Masuaku A. | Injury
Tottenham v Burnley (Saturday, 16:00 CET)
WON'T PLAY
Craig M. | Injury
Dragusin R. | Knee Injury
Gil B. | Knee Injury
Kulusevski D. | Knee Injury
Maddison J. | Knee Injury
Solomon M. | Calf Injury
Takai K. | Foot Injury
Amdouni Z. | Knee Injury
Beyer J. | Hamstring Injury
Humphreys B. | Thigh Injury
Manuel Hedilazio B. | Achilles Tendon Injury
DOUBTFUL
Udogie D. | Knee Injury
Dubravka M. | Shoulder Injury
Flemming Z. | Muscle Injury
Roberts C. | Injury
Wolves v Man City (Saturday, 18:30 CET)
WON'T PLAY
Chiwome L. | Knee Injury
Gonzalez E. | Knee Injury
Mosquera Y. | Knee Injury
Echeverri C. | Ankle Injury
Kovačić M. | Achilles Tendon Injury
DOUBTFUL
Silva F. | Hamstring Injury
Foden P. | Ankle Injury
Rodri Groin | Injury
Wilson-Esbrand J. | Calf Injury
Chelsea v Crystal Palace (Sunday, 15:00 CET)
WON'T PLAY
Colwill L. | Knee Injury
Mudryk M. | Suspended
Doucoure C. | Knee Injury
Kporha C. | Back Injury
Matheus Franca | Muscle Injury
Nketiah E. | Muscle Injury
Riad C. | Knee Injury
DOUBTFUL
Badiashile B. | Knock
Chalobah T. | Ankle Injury
Kamada D. | Knee Injury
Nottingham Forest v Brentford (Sunday, 15:00 CET)
WON'T PLAY
N/A
Gustavo Nunes | Hamstring Injury
Maghoma P. | Injury
Wissa Y. | Coach's decision
DOUBTFUL
Dominguez N. | Knee Injury
Man Utd v Arsenal (Sunday, 17:30 CET)
WON'T PLAY
Martinez Li. | Knee Injury
Gabriel Jesus | Knee Injury
DOUBTFUL
Heaven A. | Injury
Onana A. | Muscle Injury
Trossard L. | Muscle Injury
Leeds v Everton (Monday, 21:00 CET)
WON'T PLAY
TBC
TBC
DOUBTFUL
TBC