The Spaniard was taken off in their 3-1 defeat to Nottingham Forest last Sunday after a collision with Morgan Gibbs-White.
Chelsea youngster Jesse Derry has been ruled out for the rest of the season as he was also withdrawn in the loss with a hefty blow to the head, cutting short his Premier League debut.
Elsewhere, Arsenal pair Jurrien Timber and Mikel Merino are still currently unavailable for the Gunners, who take their title pursuit to relegation-threatened West Ham.
Liverpool v Chelsea (Saturday, 13:30 CET)
WON'T PLAY
Bajcetic | Hamstring Injury
Bradley | Knee Injury
Ekitike | Achilles Tendon Injury
Endo | Foot Injury
Leoni | Knee Injury
Salah | Thigh Injury
Derry | Concussion
Estêvão | Hamstring Injury
Mudryk | Suspended
Sanchez | Concussion
DOUBTFUL
Alisson | Muscle Injury
Isak | Muscle Injury
Mamardashvili | Knee Injury
Garnacho | Inactive
Gittens | Muscle Injury
Neto | Inactive
Brighton v Wolves (Saturday, 16:00 CET)
WON'T PLAY
Tzimas | Knee Injury
Webster | Knee Injury
Chiwome | Knee Injury
Gonzalez | Knee Injury
Johnstone | Knock
DOUBTFUL
Gomez | Knee Injury
March | Muscle Injury
Milner | Injury
Wieffer | Injury
Krejci | Neck Injury
Sa | Ankle Injury
Fulham v Bournemouth (Saturday, 16:00 CET)
WON'T PLAY
Iwobi | Injury
Sessegnon | Hamstring Injury
Cook | Hamstring Injury
Jimenez | Suspended
Soler | Hamstring Injury
DOUBTFUL
Berge | Illness
Kevin | Foot Injury
Kluivert | Knee Injury
Sunderland v Manchester United (Saturday, 16:00 CET)
WON'T PLAY
Ballard | Red Card
Mundle | Hamstring Injury
de Ligt | Back Injury
DOUBTFUL
Angulo | Muscle Injury
Traore | Knee Injury
Sesko | Leg Injury
Manchester City v Brentford (Saturday, 18:30 CET)
WON'T PLAY
Dias | Muscle Injury
Gvardiol | Broken Leg
Carvalho | Knee Injury
Milambo | Knee Injury
DOUBTFUL
Rodri | Groin Injury
Henderson | Knock
Henry | Muscle Injury
Burnley v Aston Villa (Sunday, 15:00 CET)
WON'T PLAY
Beyer | Hamstring Injury
Cullen | Knee Injury
Roberts | Muscle Injury
Kamara | Knee Injury
DOUBTFUL
Alysson | Muscle Injury
Onana | Calf Injury
Crystal Palace v Everton (Sunday, 15:00 CET)
WON'T PLAY
Doucoure | Knee Injury
Nketiah | Thigh Injury
Branthwaite | Hamstring Injury
Grealish | Foot Injury
Gueye | Injury
DOUBTFUL
Guessand | Knee Injury
Sosa | Injury
Nottingham Forest v Newcastle (Sunday, 15:00 CET)
WON'T PLAY
Boly | Knee Injury
Hudson-Odoi | Injury
John Victor | Knee Injury
Savona | Knee Injury
Krafth | Knee Injury
Livramento | Thigh Injury
Miley | Broken Leg
Schar | Ankle Injury
DOUBTFUL
Abbott | Concussion
Aina | Injury
Murillo | Muscle Injury
West Ham v Arsenal (Sunday, 17:30 CET)
WON'T PLAY
Fabianski | Back Injury
Merino | Foot Injury
Timber | Ankle Injury
Tottenham v Leeds (Monday, 21:00 CET)
WON'T PLAY
TBC
TBC
DOUBTFUL
TBC