Sweden had already made a strong start to their qualifying campaign with a 33-24 victory over Greece, and in front of a sold-out arena, put on a show for the crowd in Luxembourg, thrashing the outsiders 50-20.
The home side actually took the lead twice early on and were only 8-6 behind after eight minutes, but from then on, Sweden brushed them aside, scoring 18 more times in the first half and conceding just four, to lead 26-10 after 30 minutes.
The Swedes did not let up after the break, going on a 14-1 run to lead by a staggering 40-11 with still around a quarter of the match to play. With the game long over as a contest, the visitors took their foot off the gas late on, as Luxembourg reached a respectable mark of 20 goals, but only as Sweden reached the half-century mark.
Twelve Swedish players got on the scoresheet, led by the eight of Ludvig Hallback, while Emil Mellegard and Axel Mansson scored six each. However, no visiting player beat the total of Samuel Itua Etute, who scored eight for the home side.
Both Swedish goalkeepers, Simon Moller and Marko Roganovic, finished with a save rate of 50% or higher, as Luxembourg suffered their heaviest defeat in a qualifier. Sweden are top of Group 8 after two matches, two points clear of Greece and North Macedonia.