16:13 CET - It hasn't been the smoothest of starts to the afternoon for Arsenal, with Bukayo Saka pulling out of the squad after picking up an injury in the warm-up and Leeds then going close to opening the scoring early on.
16:01 CET - Bayer Leverkusen have taken charge in Frankfurt courtesy of a quickfire double from Arthur and Malik Tillman.
15:54 CET - Real Oviedo finally win again! They've claimed their first victory in 16 games thanks to Ilyas Chaira, who has scored the only goal of the game to take them past Girona.
15:01 CET - Premier League leaders Arsenal will kick off against Leeds in an hour, and the big team news is that captain Martin Odegaard has been dropped for Kai Havertz, who makes his first league start since the opening day of the season.
14:47 CET - It's goalless at the break between Real Oviedo and Girona, with an extremely flat half of football seeing the sides take just one shot each.
14:30 CET - It's a big afternoon in the Bundesliga, with third-placed Hoffenheim, fourth-placed RB Leipzig and sixth-placed Bayer Leverkusen all in action in an hour's time.
Here's how they'll line up for their games:
13:00 CET - The first match this weekend is from LaLiga as the league's bottom side Real Oviedo host Girona in an hour.
Team news is in from that clash:
11:00 CET - Good morning and welcome to the weekend! This Saturday promises a great deal as some of Europe's biggest clubs are in action and we can't wait to see how it all unfolds.
There is so much to look forward to today in the Premier League. League leaders Arsenal start the day off at 16:00 CET as they face a tough test at Leeds United. The Gunners need a response after their shock defeat against Manchester United last weekend which brought an end to their unbeaten season at the Emirates.
That is followed by a crucial London derby as West Ham United host Chelsea in a match with big ramifications at both ends of the table.
Check out Flashscore's preview of that clash here.
There is also a late kick-off in the Premier League to look forward to today as Liverpool host rivals for Champions League qualification Newcastle United from 21:00 CET.
Aside from a big day in the Premier League, Bundesliga leaders Bayern Munich take on Hamburger SV from 18:30 CET as they look to inflict more pain on the newly-promoted side after winning big against them earlier in the season.
Follow all the Bundesliga action here.
Over in Serie A, holders Napoli host relegation-battling Fiorentina in a big match for both sides.
Napoli's title challenge has taken a big dent in recent weeks and after crashing out of the Champions League midweek, their supporters will be desperate to see their side get back on track today. Fiorentina, meanwhile, remain in the Serie A relegation zone and are also in need of three points.
Follow Serie A with Flashscore.
Finally in LaLiga, Champions League hopefuls Villarreal travel to Osasuna before Diego Simeone's Atletico Madrid take on Levante at 18:30 CET. Rounding up the night are the champions and league leaders Barcelona, as Hansi Flick's side travel to Elche from 21:00 CET.